Question Solved1 Answer ​​​​​​​ A   B Caffeine, a central nervous system (CNS) stimulant   Ibuprofen, a non-steroidal anti-inflammatory drug     Question 1)Reproduce the structures and indicate the hybridisation states (e.g. sp, sp2, sp3) of each of the carbon atoms in both compound A and compound B. QUESTION 2)Caffeine is known as an alkaloid. It is poorly soluble in cold water. Give the definition of an alkaloid (citing the source used) and suggest a simple chemical treatment that would help solubilise caffeine in water. question 3) Reproduce compound B of Figure Q1 and label with a * the chiral carbon. QUESTION 4) Redraw the 3D structure of B, then circle and label the groups around the chiral centre according to the Cahn-Ingold-Prelog (CIP) priority rules. Assign the resulting R or S stereodescriptor to the chiral centre. QUESTION 5) Draw the 3D structure of the mirror image of the ibuprofen structure on Figure Q1 ​​​​​​​QUESTION 6 Ibuprofen is fact given as a 1:1 mixture of both R and S stereoisomers. Suggest an experimental technique that can be used to verify whether a tablet contains equal amounts of those isomers. What is such a mixture called?

KLJAHQ The Asker · Chemistry

​​​​​​​

A

 

B

Caffeine, a central nervous system (CNS) stimulant

 

Ibuprofen, a non-steroidal

anti-inflammatory drug

 

 

Question 1)Reproduce the structures and indicate the hybridisation states (e.g. sp, sp2, sp3) of each of the carbon atoms in both compound A and compound B.

QUESTION 2)Caffeine is known as an alkaloid. It is poorly soluble in cold water. Give the definition of an alkaloid (citing the source used) and suggest a simple chemical treatment that would help solubilise caffeine in water.

question 3) Reproduce compound B of Figure Q1 and label with a * the chiral carbon.

QUESTION 4) Redraw the 3D structure of B, then circle and label the groups around the chiral centre according to the Cahn-Ingold-Prelog (CIP) priority rules. Assign the resulting R or S stereodescriptor to the chiral centre.

QUESTION 5) Draw the 3D structure of the mirror image of the ibuprofen structure on Figure Q1

​​​​​​​QUESTION 6 Ibuprofen is fact given as a 1:1 mixture of both R and S stereoisomers. Suggest an experimental technique that can be used to verify whether a tablet contains equal amounts of those isomers. What is such a mixture called?

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Explanation:Organic compounds are consist of carbon atoms covalently bonded with other atoms like nitrogen, oxygen and hydrogen. Structure of an organic compound helps in identifying the functional groups present in it. Step2/2.gkwtCW{margin:0;font-family:"Aspira Webfont","Helvetica","Arial",sans-serif;display:-webkit-box;display:-webkit-flex;display:-ms-flexbox;display:flex;-webkit-flex-direction:column;-ms-flex-direction:column;flex-direction:column;gap:16px;}/*!sc*/data-styled.g367[id="sc-z3f5s1-0"]{content:"gkwtCW,"}/*!sc*/.iIwMoS{white-space:pre-wrap;}/*!sc*/data-styled.g369[id="sc-1aslxm9-0"]{content:"iIwMoS,"}/*!sc*/.fzJtOB{text-align:start;}/*!sc*/data-styled.g371[id="sc-1aslxm9-2"]{content:"fzJtOB,"}/*!sc*/.aczzN{line-height:1;font-size:80%;}/*!sc*/data-styled.g394[id="sc-1r1de4b-3"]{content:"aczzN,"}/*!sc*/.hOZehF{margin:0;font-family:"Aspira Webfont","Helvetica","Arial",sans-serif;}/*!sc*/data-styled.g398[id="sc-9wsboo-0"]{content:"hOZehF,"}/*!sc*/.evjWEY{padding:0 1.5px;}/*!sc*/data-styled.g399[id="sc-9wsboo-1"]{content:"evjWEY,"}/*!sc*/.lhIoTe{margin:0;font-size:1rem;}/*!sc*/data-styled.g400[id="sc-1swtczx-0"]{content:"lhIoTe,"}/*!sc*/.dirqSb{margin:0;font-family:"Aspira Webfont","Helvetica","Arial",sans-serif;}/*!sc*/data-styled.g429[id="sc-1wwe652-0"]{content:"dirqSb,"}/*!sc*/.dZTFxH{background-color:#fff;font-size:16px;}/*!sc*/data-styled.g430[id="sc-1wwe652-1"]{content:"dZTFxH,"}/*!sc*/.kZhTRC{-webkit-user-select:none;-moz-user-select:none;-ms-user-select:none;user-select:none;}/*!sc*/.XCduS{-webkit-user-select:none;-moz-user-select:none;-ms-user-select:none;user-select:none;baseline-shift:-70%;font-size:65%;}/*!sc*/data-styled.g431[id="sc-1wwe652-2"]{content:"kZhTRC,XCduS,"}/*!sc*/.iHelzO{margin:0;font-family:"Aspira Webfont","Helvetica","Arial",sans-serif;line-height:normal;}/*!sc*/data-styled.g433[id="sc-1sugbjn-0"]{content:"iHelzO,"}/*!sc*/.kkKaFK{margin-top:14px;}/*!sc*/data-styled.g437[id="sc-1sugbjn-4"]{content:"kkKaFK,"}/*!sc*/.iQllJf{margin-top:14px;}/*!sc*/data-styled.g438[id="sc-1sugbjn-5"]{content:"iQllJf,"}/*!sc*/The given compounds A and B are caffeine and ibuprofen. The structures of compounds are represented as follows:CNCNCCCH3CH3OONNCHCH3CaffeineCompound ACHCCHCHCHCHCH3CCCH2CHCH3OHOCH3IbuprofenCompound BNow, from the above structures it can be seen that in compound A (caffeine), there is one carbonyl group, an amine group, an alkene group, and an amide group present. In compound B (Ibuprofen), there is one carboxylic acid group, propyl group, phenyl ring, and isobutyl group present. Now, determine the hybridization of each carbon atom in compounds A and B by counting the total number of atoms bonded to it. In compound A (Caffeine):CONOCH3NCCCNNCH3HCH3Csp2sp3sp3sp3sp2sp2sp2sp2Thus, there are three sp3 and six sp2 hybridized carbon atoms in the compound A. In compound B (Ibuprofen):OCH2CHCH3CCH3CHOHCHCH3CHCHCCCHsp2sp3sp2sp3sp3sp3sp3sp3sp2sp2sp2sp2sp2Thus, there are six sp3 and seven sp2 hybridized carbon atoms in the compound B. Explanation:mjx-container[jax="CHTML"] { line-height: 0;}mjx-container [space="1"] { margin-left: .111em;}mjx-container [space="2"] { margin-left: .167em;}mjx-container [space="3"] { margin-left: .222em;}mjx-container [space="4"] { margin-left: .278em;}mjx-container [space="5"] { margin-left: .333em;}mjx-container [rspace="1"] { margin-right: .111em;}mjx-container [rspace="2"] { margin-right: .167em;}mjx-container [rspace="3"] { margin-right: .222em;}mjx-container [rspace="4"] { margin-right: .278em;}mjx-container [rspace="5"] { margin-right: .333em;}mjx-container [size="s"] { font-size: 70.7%;}mjx-container [size="ss"] { font-size: 50%;}mjx-container [size="Tn"] { font-size: 60%;}mjx-container [size="sm"] { font-size: 85%;}mjx-container [size="lg"] { font-size: 120%;}mjx-container [size="Lg"] { font-size: 144%;}mjx-container [size="LG"] { font-size: 173%;}mjx-container [size="hg"] { font-size: 207%;}mjx-container [size="HG"] { font-size: 249%;}mjx-container [width="full"] { width: 100%;}mjx-box { display: inline-block;}mjx-block { display: block;}mjx-itable { display: inline-table;}mjx-row { display: table-row;}mjx-row > * { display: table-cell;}mjx-mtext { display: inline-block;}mjx-mstyle { display: inline-block;}mjx-merror { display: inline-block; color: red; background-color: yellow;}mjx-mphantom { visibility: hidden;}_::-webkit-full-page-media, _:future, :root mjx-container { will-change: opacity;}mjx-assistive-mml { position: absolute !important; top: 0px; left: 0px; clip: rect(1px, 1px, 1px, 1px); padding: 1px 0px 0px 0px !important; border: 0px !important; display: block !im ... 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